Earnest — Supplement & Peptide Intelligence
Science-backed supplement guidance
Rooted in 5,000 years of Ayurvedic wisdom

Thousands of
supplements
& peptides.
Find yours.

Thousands of supplements & peptides. Find yours.

The oldest
medicine
on earth.
Personalized to you.

The oldest medicine on earth. Personalized to you.

Tell us how you feel. We find the herbs matched to your constitution, rooted in the Charaka Samhita and validated by modern clinical research.
How it works
1
Ask anything
Type any goal, symptom, or question.
2
See science-backed picks
Specific brands and doses carefully vetted, with every claim cited.
3
Save and refine your stack + personalized report
We learn from who you are and what you're taking to improve every answer.
★Personalized report you can download anytime.
4,000+
Supplements and peptides reviewed
Research-backed
Every rec cites real human studies
9 verifications
Per brand before Earnest recommends it
Ayurvedic too
Toggle for herbs from 5,000 years of classical texts
5,000 years
Of Ayurvedic wisdom, personalized to you
3 classical texts
Charaka Samhita · Sushruta Samhita · Ashtanga Hridayam
Peer-reviewed
Cross-referenced with AIIMS and CSIR clinical research
Curated brands
Organic India, Banyan Botanicals, Himalaya, Pukka
E·O
Earnest
What are you trying
to figure out?What do you want to figure out?
Start your search
2 free searches · Sign in to personalize

From your question to a stack that works.

1
Ask
Type a symptom, a goal, or anything you want to figure out.
2
See what works
Specific picks with citations to real human studies. Dosing and which brands to buy.
3
82% covered 1 flag
Save what you take
Earnest tracks your routine, watches for medication interactions, shows where your stack covers your goal and where it falls short, and tunes every future answer to your situation.
What you'll see
Query "I'm tired in the afternoon and want to feel sharper."
L-Tyrosine Strong evidence
Sustained focus and stress resilience. Multiple human RCTs in fatigued and stressed populations.
Rhodiola Rosea Good evidence
Adaptogen with multiple RCTs on mental and physical fatigue. Faster onset than most.
CoQ10 (Ubiquinol) Early research
Mitochondrial cofactor. Helpful especially after age 40 and with statin use.
Plus brand picks, dosing, interactions, and your personalised plan in real results.
The moment

Your goal,
mapped.

Name what you are working toward. Earnest shows the biological pathways it takes to get there, which ones your current stack covers, and which ones it misses.

Most people are surprised. They were closer to one pathway than they thought, and missing two others entirely.

EXAMPLESara's stack · age 42 · keto
Goal
Sleep
1 of 3 pathways covered
33%
Relaxation & wind-down
Magnesium Glycinate · L-Theanine
Covered
Sleep onset signaling
Nothing in your stack targets this
Gap
Deep sleep maintenance
Nothing in your stack targets this
Gap
Built on rigor

4,000+ compounds.
10,000+ studies.
Zero ads.

Earnest is one of the most carefully curated science and interaction databases for supplements, peptides, medications, and Ayurvedic herbs. Every compound is cross-referenced against published human research and the classical texts, reviewed by clinicians, and updated as the evidence evolves.

4,000+
Supplements, peptides, and medications in the database
10,000+
Peer-reviewed human studies referenced across recommendations
9
Independent checks every brand passes before Earnest recommends it
Peer-reviewed
Every recommendation ties to human clinical research. No opinions, no supplement-brand talking points.
Clinician input
Built with practicing physicians. Interaction rules are reviewed by humans, not scraped from forums.
Never paid
Earnest is never paid to recommend a brand. Rankings are driven by evidence and safety, not partnerships.
Who's behind it

Founded by a Johns Hopkins School of Medicine PhD.

Earnest is built with input from physicians and grounded in published clinical research. The database evolves as the evidence does. You get the most current read on your stack, every time.

Name a goal. See the map.
Our approach
The science behind Earnest
Earnest started from a frustration most of us share — standing in a supplement aisle, or staring at a dozen bottles at home, with no real idea whether they're doing anything, whether the dose is right, or why you'd take one over another. We thought there had to be a better way to bring rigorous science to everyday decisions.
Who built this
Earnest was created by a PhD in Biomedical Engineering from Johns Hopkins University — with a research background in how compounds interact with human biology at a molecular level.
Every recommendation framework has been developed in consultation with physicians from University of Pennsylvania, Johns Hopkins, Stanford, and Massachusetts General Hospital — spanning internal medicine, endocrinology, and longevity medicine.
Shaped in close collaboration with Gianluca Sansone and Edoardo Alessandri — bringing decades of perspective from one of the most respected families in wellness and fitness.
On peptides
Peptides are one of the most exciting — and most confusing — areas in longevity medicine right now. The research is genuinely promising, but there is an enormous amount of noise: unreliable sourcing, unverified dosing protocols, and marketing that outpaces the evidence. Earnest cuts through this by citing only peer-reviewed human trials, flagging where evidence is early-stage, and being explicit about what remains unknown. We'd rather tell you "the evidence is limited" than overstate a compound's case.
A note on caution
The supplement and peptide landscape is evolving rapidly — regulations are changing, new research is published constantly, and what's available today may be classified differently tomorrow. Earnest is not a replacement for your doctor. We use data, mathematics, and the latest published research to help you ask better questions and make more informed choices — but always in conversation with a qualified healthcare provider, especially for anything outside standard OTC supplements.
Welcome to Earnest.
Sign in for unlimited searches, your personal supplement plan & saved plans.
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Your data is never sold or shared.
Earnest Pro
Your data.
Your picture.
Free tells you what to take. Pro tells you exactly which brand, why, and what your personal data says about your situation.
What you get Free Pro
Supplement searches
Science-backed recs for any symptom or goal
 Unlimited Unlimited
Earnest's #1 brand pick
One verified pick per supplement, fully explained
 ✓ ✓
Supplement cabinet
Track what you take, see your gaps
 ✓ ✓
Full brand comparison
Every brand ranked by recalls, testing and price per dose
 No ✓
Goal pathway analysis
For each goal, which pathways you cover, what's missing, what to add
 Teaser only ✓ Full
Peptide recommendations
BPC-157, TB-500, GHK-Cu and more, personalised to your goals
 No ✓
Blood work analysis
Upload your labs, Earnest adjusts recommendations to your actual values
 No ✓
Label scanner
Photo any bottle, added to your cabinet instantly
 No ✓
Protocol export
PDF, email, or share with your doctor
 No ✓
Ananda ayurvedic search
Free access to our sister platform for traditional medicine
 No ✓ Free
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Annual
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per year
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